Rias Ali MD PLLC · Patient Education
Download PDF Call (727) 943-5200
Language
Accessibility
Mitral Regurgitation Guide

Understanding Mitral Regurgitation

When the mitral valve leaks — primary vs secondary, and what to do

Understanding Mitral Regurgitation cover diagram
QR code linking to https://go.riasalimd.com/mr-guide
Scan to save this guide

Point your phone camera at the QR code, or visit go.riasalimd.com/mr-guide

Written by Rias KS Ali, MD FACC, Board-Certified Interventional Cardiologist · 4740 Mile Stretch Drive, Holiday FL 34690 · Updated August 2026

Online: https://go.riasalimd.com/mr-guide

Names & Terms You Will Hear

Plain-language meanings for the terms your care team may use.

TermMeaning
Mitral regurgitation (MR)The medical name. The mitral valve does not close all the way, so blood leaks backward.
Mitral insufficiencySame thing. An older term.
Leaky mitral valveThe plain-language name. This is what most patients hear.
Primary (degenerative) MRThe valve itself is broken — a torn cord, a floppy leaflet, or scarring.
Secondary (functional) MRThe valve is fine. But the heart around it has stretched and pulls the valve open.
Mitral valve prolapse (MVP)A floppy leaflet bulges back into the top chamber. It is a common cause of primary MR.
Barlow diseaseA type of MVP with thick, bulky leaflets. It carries a higher MR risk.
Fibroelastic deficiencyA type of MVP in older adults. The cords are thin and weak and can snap.

What Is Mitral Regurgitation?

A real echocardiogram with color Doppler — the bright jet is blood leaking backward through the mitral valve with each heartbeat. Image: CASE (Cardiovascular Imaging Case Reports), 2024 (CC BY 4.0).
A real echocardiogram with color Doppler — the bright jet is blood leaking backward through the mitral valve with each heartbeat. Image: CASE (Cardiovascular Imaging Case Reports), 2024 (CC BY 4.0).

Why It Matters

Risk Factors

Knowing your personal risks helps your care team take extra precautions.

Risk FactorWhy It Increases Risk
Mitral valve prolapse (MVP)A floppy or thick leaflet bulges back. Over years, the cords can stretch or snap, and MR gets worse.
Prior heart attackScar in the heart wall, or harm to a small muscle, can pull a leaflet open. This causes secondary MR.
Heart failure / weak, stretched heartA stretched left ventricle pulls the leaflets apart. The valve itself is fine.
Rheumatic heart diseaseA childhood strep throat can scar and stiffen the valve. It is still common around the world.
Valve infection (endocarditis)It can wreck a leaflet in days or weeks. This is a surgical emergency.
Inherited tissue disease (Marfan, Ehlers-Danlos, Loeys-Dietz)These weaken the valve cords and leaflets. MVP and snapped cords happen more often.
Atrial fibrillation (AFib)Ongoing AFib stretches the top chamber and the valve ring. That makes any MR worse.
Older ageWorn-out valves and snapped cords are more common as we age.

Treatment Options

Shown in English for your safety — this section is not automatically translated. Confirm with your doctor or call the office.

Risks, Benefits, and Alternatives

Shown in English for your safety — this section is not automatically translated. Confirm with your doctor or call the office.

Every choice has trade-offs. Use this table to start the shared decision conversation with your care team.

OptionRisksBenefitsAlternatives
Watch and wait, with a yearly echo, for mild or moderate MRMR may grow between visits. A cord can snap on its own, but this is rare.No procedure and no drug. Most mild or moderate MR stays steady for years.Surgery sooner; or medicine.
Surgery to repair the valve (the top choice for primary MR)Open-heart surgery. Stroke risk near 1 in 100. Also bleeding, infection, and a 6 to 8 week recovery. A redo is rarely needed.The best choice for a worn-out valve. It lasts a long time and keeps your own valve. No warfarin.Replace the valve; or TEER if you cannot have surgery.
Surgery to replace the valveSame risks as a repair, plus valve risks. A metal valve needs warfarin for life. A tissue valve needs a redo in 10 to 15 years.Used when the leaflets cannot be fixed, such as a hard, chalky valve or a scarred valve.Repair if the valve allows; or TEER if you are high-risk.
TEER (MitraClip) — a clip placed through a thin tubeSome leak may stay. A leaflet may slip off the clip. The leg vein can bleed. Not every valve fits a clip.No open surgery. Quick recovery. The COAPT trial showed longer life in chosen secondary MR.Surgery if you are a good fit; or medicine alone.
Heart-failure medicine for secondary MRSide effects from these drugs, such as low blood pressure, kidney strain, or high potassium.It can shrink the leak by 30% to 50%. It is the first step in current guidelines.Add TEER if a bad leak lasts; or weigh a transplant.

Common Misconceptions

MythReality
"All mitral regurgitation is the same."Primary and secondary MR are two different problems with two different fixes. Primary is a valve problem. We repair it. Secondary is a heart-muscle problem. We treat it first with heart-failure medicine.
"Mitral valve prolapse always needs surgery."Most MVP causes only a mild leak and never needs a fix. Only a few cases grow into severe MR. Those get surgery, but only once symptoms or warning numbers show up.
"Surgery always means cracking the chest."Many mitral repairs today use a small cut on the right side. And TEER skips surgery for good — it works through a vein in the leg.
"If I feel fine, my MR cannot be severe."Many people with severe MR feel fine for years. The heart makes up for it. By the time you feel it, the heart may be hurt. That is why we watch echo numbers, not just how you feel.
"A MitraClip is just as good as surgery."TEER is great for the right patient — older, high-risk, or chosen secondary MR. But a surgical repair lasts longer. It is still the top choice for younger patients with a worn-out valve.
"My MR will get better on its own."Severe primary MR does not get better. Secondary MR can shrink with heart-failure medicine — but only if you take it.

Possible Complications

Knowing what can go wrong helps you spot problems early. Most complications are uncommon, especially with treatment.

Where / WhatWhat Can Happen
Atrial fibrillation (AFib)A stretched top chamber sets off AFib. AFib makes MR worse and raises stroke risk.
Heart failureThe steady extra blood load wears out the left ventricle. It can lead to heart failure over time.
High lung pressureThe backed-up pressure harms the lung's blood vessels. It can stick around even after we fix the MR.
Valve infection (endocarditis)Hurt or man-made valves face a higher risk. We give antibiotics before some dental work.
StrokeIt can come from AFib, or from a clot that breaks off a hurt valve.
A cord snaps all at onceThis causes a sudden bad leak and a flooded lung. It is an emergency. We often operate within days.
Waiting too long for surgeryIf the pump drops below 50% or the chamber reaches 50 mm across, the heart may not bounce back, even after a perfect repair.

Points to Know

Shown in English for your safety — this section is not automatically translated. Confirm with your doctor or call the office.

If you remember nothing else, remember these key points.

When to Call Us — and When to Call 911

Shown in English for your safety — this section is not automatically translated. Confirm with your doctor or call the office.

If you are not sure, call. We would rather hear from you twice than miss a real problem.

Office: (727) 943-5200

Trusted Resources

Independent, evidence-based pages we recommend for deeper reading.

Sources Used to Build This Guide

Scan to visit RiasAliMD.com
Visit RiasAliMD.com
Scan to save Dr. Rias Ali contact
Save Contact

Read this guide in your language

EspañolSpanishالعربيةArabic中文ChineseFrançaisFrenchDeutschGermanΕλληνικάGreekKreyòl AyisyenHaitian CreoleעבריתHebrewहिन्दीHindiItalianoItalian
日本語Japanese한국어KoreanമലയാളംMalayalamفارسیPersianPolskiPolishPortuguêsPortugueseРусскийRussianTagalogTagalogதமிழ்TamilతెలుగుTeluguTiếng ViệtVietnamese

Automatic translation — not reviewed by a qualified medical translator and it may contain errors. The English version is the official one. For your medicines, symptoms, or an emergency, use the English or Spanish guide or call the office. In an emergency, call 911.